Paroxetine (also known by the trade name Paxil among others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) type.

In a clinical trial in healthy subjects, a potent inhibitor of CYP3A4 (ketoconazole) increased aripiprazole AUC and Cmax by 63 and 37 , respectively.

Specifically, sarin is a potent inhibitor of acetylcholinesterase, an enzyme that degrades the neurotransmitter acetylcholine after it is released into the synaptic cleft.

Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.

Humphry Davy discovered the use of platinum in catalysis.

Citalopram ( or brand names Celexa, Cipramil) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class.

Powerful and easy to use calculator

Imagination is a very potent tool.

Lead is a potent neurotoxin.

Tom has a very powerful voice.

There is also some evidence pointing towards moclobemide possessing neuroprotective properties.

Yves Behar's supercharged motorcycle design

If you take the obese mouse and give it an angiogenesis inhibitor, it loses weight.

What is it about transgression that makes desire so potent?

These guys make the loudest car stereo in the world.

Language really is the most potent trait that has ever evolved.

You will need a powerful computer to be able to run this game.

This field of phylogenetics is a powerful tool in evolutionary biology.

Their sense of smell for tracking is second only to that of the Bloodhound.

Captopril (rINN) is an angiotensin converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure.

Franka Potente (born 22 July 1974) is a German film actress and singer.

Some forms of this respond to treatment with a glucosidase inhibitor, which slows starch digestion.

So that is the program, embarrassingly simple, but as we're going to see, extremely powerful.

And you can see clearly that the teas vary in their potency from less potent to more potent.

And with a more powerful telescope, you'll be able to see stars, and planets.

Further, the spices with the most potent antimicrobial activity tend to be selected.

For his admirers and critics alike, Meles leaves behind a potent political legacy.

Aftermath Truman had mentioned an unspecified powerful new weapon to Stalin during the conference.

For example, the drug methotrexate is a competitive inhibitor of the enzyme dihydrofolate reductase, which catalyzes the reduction of dihydrofolate to tetrahydrofolate.

That wave is much larger, much more powerful, and that's of course the wave of technology.

It is a much more potent sentiment than a simple liking for another.

In addition, mianserin also appears to be a potent antagonist of the neuronal octopamine receptor.

Photo from Sina Weibo. Despite the public anger, the chilling effect of the crackdown has reined in different voices online.

The binding of an inhibitor can stop a substrate from entering the enzyme's active site and or hinder the enzyme from catalyzing its reaction.

Design Overview The T 34 had well sloped armour, a relatively powerful engine, and wide tracks.

Mechanism The toxin is the protein botulinum toxin produced under anaerobic conditions (where there is no oxygen) by the bacterium Clostridium botulinum .

Tsar Bomba ( Tsar of bombs ) is the nickname for the AN602 hydrogen bomb, the most powerful nuclear weapon ever detonated.

Aero Boero AB 115 150 Version with more powerful 150 hp Lycoming O 320 engine.

The blast was potent because the wave front was in between two buildings or plazas which had lead to the Islamabad Courts.

Some of this carbon is transferred to the ocean and other portions of the globe through the global carbon cycle.

Upon discontinuation of the CYP2D6 or 3A4 inhibitor, the dosage of ABILIFY should be increased to the level prior to the initiation of the concomitant therapy.

When the CYP3A4 or CYP2D6 inhibitor is withdrawn from the combination therapy, aripiprazole dose should then be increased (see section 4.5).

97 Upon discontinuation of the CYP2D6 or 3A4 inhibitor, the dosage of ABILIFY should be increased to the level prior to the initiation of the concomitant therapy.

However, an extremely high concentration of molybdenum reverses the trend and can act as an inhibitor in both purine catabolism and other processes.

In addition to mood disorders, persons may exhibit manic behavior increased by drug intoxication (notably stimulants, such as cocaine and methamphetamine), medication side effects (notably SSRIs), and malignancy (the worsening of a condition).